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Session 39
Thursday, September 3
10:30 am – 12:30 pm
Room: Bosio
Esophageal Pathology: Pot-pourri
Chair: Robert H. Riddell (Canada)
Discussant: Henry D. Appelman (USA)
Esophageal carcinoma
- Why are pyloric gland adenomas found in Barrett’s esophagus? Are they a source of non-intestinal carcinomas? Rhonda Yantiss (USA)
- Does the phenotype of esophageal adenocarcinomas, intestinal phenotype vs. others, matter?
Dhanpat Jain (USA)
- What is the recurrence rate for non-dysplastic BE and dysplastic BE post endoscopic resection.
Does grade matter? Henry D. Appelman (USA)
- What are the mechanisms of recurrence post – endoscopic ablation? Are there any data to support them? Ilke Nalbantoglu (USA)
- Do buried subsquamous glands pose a risk of metastasis? If so when? Dhanpat Jain (USA)
- Does multilayered epithelium ever get mistaken for LGD? If so, why? Robert H. Riddell (Canada)
- What stimulates the development of pancreatic metaplasia in the cardia or lower esophagus? Is it really a metaplasia or is it a variant of normal? Rupert Langer (Switzerland)
- Is it possible to separate carcinoma cuniculatum from verrucous carcinomas, especially in biopsies? Does it matter? Monika Tripathi (Canada)
- Are Merkel cells found in the normal esophagus? If so, are we missing Merkel cell carcinomas and why? Paul E. Swanson (Canada)
Autophagy in esophageal diseases
- What is autophagy and can we/should we detect it in routine pathology specimens?
Rupert Langer (Switzerland)
- What is the role of autophagy in GERD/inflammatory esophageal disease? Cathy S. Streutker (Canada)
- What role may autophagy play in the interaction pro and anti-apoptotic pathways in esophageal malignancies. Paul E. Swanson (Canada)
Sloughing esophagitis
- What are the histological criteria for sloughing esophagitis? What are the minimal criteria on which this diagnosis can be made? Henry D. Appelman (USA)
- What are the causes and endoscopic criteria for sloughing esophagitis? Fouad J. Moawad (USA)
- How should sloughing esophagitis be reported (assuming the person receiving the report may never have heard of it). Joanna Gibson (USA)
Lymphocytic esophagitis:
- What are the known or suspected causes of lymphocytic esophagitis? Xuchen Zhang (USA)
- Are there criteria for a diagnosis of lymphocytic esophagitis? Which subsets of cells are involved?
Mikhail Lisovsky (USA)
- Should lymphocytic esophagitis be reported at all? If so how? Maria Westerfoff (USA)
Scientific Information:
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